Microscopy

Cinematic visual effects created for film and television utilize software with the same mathematical image processing power found in scientific visualization. Here are some examples of microscopy visualizations using visual effects software that can access floating point pixel value. Unlike scientific software, visual effects software has a multitude of additional functionalities to render and clean up small resolution microscopy footage and output in film ready HD resolution.

Confocal Data Visualization

Immunofluorescence experiments are often captured on highly sensitive monochrome cameras in 12, 14 or 16bit data formats. Visualization Scientists create composite images by combining layered imagery of different cellular structures into red, green and blue color channels. This allows them to visually delineate cellular structures in a single image. From this composite, scientists can deduce experimental results and communicate new insights. Since many scans traverse a depth of tissue, visualizations of cross-sections tell the story of both cellular volume and diversity.

cell culture microscopy

Microscopy and Cinematic Color Correction

Often times, raw datasets are poor quality, certainly not for use in large format media displays like television or film. The output from most scientific software, while excellent at performing complex calculations like cell counting and volumetric reconstructions, is limited by the quality of the dataset. This is when visual effect software comes to the rescue. Just like film undergoes a cinematic color correction process, visualization scientists can use visual effects software to transform low-quality microscopy into the high-quality film.

Resizing, Sharpening, and Resampling Data over Time

When scans much smaller in resolution than broadcast video production requires, it’s important to have a visual effect professional acutely resize and sharpen microscopy data.

Plasma membranes, organelles, or nuclear DNA are stored in as layers of black and white data that needs to be colored, combined, and scaled up to broadcast ready resolution. The key to providing the highest quality assets is to colorize the different layers while resizing and sharpening footage.

3D Microscopy Animation

Not all microscopy data sets can tell complex stories that match a narrative message. 3D medical animations create these narrative scientific stories. They can depict cells and molecules in the same visual style used in med school textbooks.

Visualization Services

Contact us if you have an interest in creating custom microscopy footage or have ideas about unique ways to integrate microscopy into an educational program.

  • Confocal Microscopy Animation
  • Fluorescence Composites
  • Cell Counting
  • 3D Volumetric
  • 3D Animation

 

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