EGFR 3D Molecular Visualization

EGFR, Biologic Animation

EGFR Receptor Dimer

Protein Description

Epidermal growth factor receptor (EGFR) exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor α (TGFα) (note, a full list of the ligands able to activate EGFR and other members of the ErbB family is given in the ErbB article). ErbB2 has no known direct activating ligand, and may be in an activated state constitutively or become active upon heterodimerization with other family members such as EGFR. Upon activation by its growth factor ligands, EGFR undergoes a transition from an inactive monomeric form to an active homodimer[7]

Inactive EGFR Tyrosine Kinase 3D Molecular Visualization

This 3D animation depicts EGFR bound by Erlotinib.

Active Mutant EGFR Tyrosine Kinase 3D Molecular Visualization

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If you’d like a desktop model of Active or Inactive EGFR, you can purchase one from our store. Prints available in multiple sizes.

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